Table 5.

Effect of heating on the physico-chemical parameters of zein nanoparticles containing various amounts of PTX.

PTX concentration (μg/ml)	Temperature (°C)	Mean size (nm)	Polydispersity Index	Zeta potential (mV)
-	30	126 ± 1	0.12 ± 0.01	-33.8 ± 2.6
	40	126 ± 2	0.13 ± 0.02	-34.7 ± 2.2
	50	128 ± 1	0.15 ± 0.02	-28.9 ± 1.2
100	30	103 ± 6	0.19 ± 0.01	-32 ± 1.1
	40	118 ± 5	0.22 ± 0.04	-34 ± 1.5
	50	129 ± 6*	0.25 ± 0.05	-30 ± 1.6
200	30	131 ± 6	0.18 ± 0.03	-29 ± 1.2
	40	133 ± 6	0.19 ± 0.02	-33 ± 1.5
	50	140 ± 5	0.21 ± 0.01	-30 ± 1.3
300	30	158 ± 5	0.21 ± 0.04	-31 ± 2.0
	40	160 ± 6	0.23 ± 0.05	-32 ± 3.0
	50	160 ± 6	0.25 ± 0.06	-31 ± 2.9

*p < 0.05 (with respect to the formulation at 30 °C).