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. 2019 Sep 9;19:232. doi: 10.1186/s12935-019-0948-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — MBD1 enhances the proliferation, invasion and migration capabilities of GBC cells in vitro. a MBD1-overexpressing cell clones were generated with GBC-SD and SGC-996 cells. b, c Overexpression of MBD1 significantly increased the colony-forming capacity of GBC-SD and SGC-996 cells. d A CCK-8 proliferation assay showed that MBD1 overexpression significantly elevated the viability of GBC-SD and SGC-996 cells. e, f Wound healing and Transwell assays showed that MBD1 promoted the invasion and migration capabilities of GBC cells. *P < 0.05, **P < 0.01