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Cessation of Ca2+ transients within most nNOS-GCaMP3 neurons during an evoked colonic migrating motor complex (CMMC), the movement of which is illustrated in the bottom trace (C). Note the relative increase in activity in cells 2, 3, 4, 6, 7, and 8 at the beginning of the CMMC, a time when smooth muscle cells exhibit hyperpolarization.
