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. 2019 Sep 10;20:704. doi: 10.1186/s12864-019-6039-9

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Proportion of age-associated CpGs residing in regions defined by gene features. The red bar represents all measured CpGs. Fisher exact tests comparing enrichment/depletion within individual categories to all categories were significant among men for first exon (p = 5.7 x 10^-6) and body (p = 0.0002) regions and among women for TSS1500 (p = 0.0337), TSS200 (p = 3.5 x 10^-5), 5′ UTR (p = 0.0307), first exon (p = 7.9 x 10^-5), body (p = 0.0003), and intergenic (p = 0.0054). Fisher exact tests comparing enrichment/depletion within individual categories between men and women were significant for TSS200 (p = 0.0016) and first exon (p = 0.0419)