Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A) LPS activates TLR4, signaling through NFκB to induce cytokines and miR-155. LPS activation also increases glycolysis, providing ATP to augment NFκB transcription and cytokine production. B) Exogenous lactic acid imported through MCT-1 suppresses glycolysis, effectively suppressing NFκB transcriptional activity.
