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Schematic diagram of protein domains of selected fusions, detailed fusion sequences, and Sanger confirmation. A: KIAA1549-BRAF and GIT2-BRAF in pilocytic astrocytoma patients. B: Two different BCR-ABL1 fusions in a chronic myeloid leukemia (CML) and a B-cell acute lymphoblastic leukemia (B-ALL) patient. C:CENPC-ABL1 in a B-ALL patient. Black arrows indicate the direction of reading frame; red arrows, the break points on mRNA level.
