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Table 2.

Analysis results for the myelokathexis (MK), cyclical (CN) and severe congenital (SCN) neutropenic patients of this study. The fraction f a of apoptotic cells was determined as before. f N , the fraction of circulating neutrophils relative to normal was based on the neutrophil count determined for each individual and a value of 4.4 × 10 3  cells/mm 3 for normal individuals ( Dancey et al. 1976 ). The fraction fT of the post‐mitotic marrow neutrophil precursor compartment (metamyelocytes and bands) was determined from actual bone marrow differentials on each patient and a normal value of 0.445 was determined from a weighted average of the figures of Dancey et al. (1976 ) (Table III, 43.2% of the total marrow neutrophilic cells were metamyelocytes and bands, n  = 13) and the control values of Chatta et al. (1996 ) (Table 2, the post‐mitotic pool constitutes 46.0% of total marrow neutrophils, n  = 13). The duration of the post‐mitotic compartment τ m was taken to be 1.2 days from Hearn et al. (1998 ) for neutropenic patients. All else as in Table 1

Diag. f a f N f T γ δ V 0 graphic file with name CPR-36-27-e007.jpg
MK 0.10 0.089 1.02 4.85 43.6 23 298.1
CN 0.23 0.172 0.494 3.6 11.9  7.9  52.4
SCN 0.11 0.044 0.135 3.56 28.8  2.4  62.8
SCN 0.10 0.014 0.045 3.61 32.4  0.83  67.6