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Table 1.

Definitions of cell kinetic parameters used in this paper

Stem cells
s ( a ) Density function of cycling stem cells
s ( aa Age distribution of cycling stem cells
s (0) Rate of entry into stem cell‐cycle
ρs(aa Probability distribution of stem cell‐cycle times
p s ( aa Apoptosis‐corrected probability distribution of stem cell‐cycle times
m ( aa Distribution of stem cell‐cycle times
M ( aa Apoptosis‐corrected distribution of stem cell‐cycle times
s Mean stem cell‐cycle time
s Effective stem cell‐cycle time
graphic file with name CPR-36-1-e110.jpg Variance of stem cell‐cycle time
φs Coefficient of variation of stem cell‐cycle time, σs/T̄s
N s Density of stem cells
f Fraction of cycling stem cells
r s Rate of stem cell division
βs Stem cell apoptotic rate
α Stem cell apoptosis correction term
Transit‐amplifying cells
t i ( a ) Density function of ith generation transit‐amplifying cells
t i ( aa Age distribution of ith generation transit‐amplifying cells
t i (0) Rate of entry into ith generation cell‐cycle
ρt(aa Probability distribution of transit‐amplifying cell‐cycle times
p t ( aa Apoptosis‐corrected probability distribution of transit‐amplifying cell‐cycle times
t Mean transit‐amplifying cell‐cycle time
s Effective transit‐amplifying cell‐cycle time
graphic file with name CPR-36-1-e111.jpg Variance of transit‐amplifying cell‐cycle time
φt Coefficient of variation of transit‐amplifying cell‐cycle time, σt/T̄t
φt Density of ith generation transit‐amplifying cells
N t Density of all transit‐amplifying cells
g Maximum number of transit‐amplifying cell generations
βt Transit‐amplifying cell apoptotic rate
Q i Probability of an ith generation transit‐amplifying cell giving two post‐mitotic cells
Pi graphic file with name CPR-36-1-e112.jpg
l A–D Frequency of transit lineages
General
a Chronological age of cells
δa Small amount of age
r Birth rate of post‐mitotic cells per unit area of skin surface
N Total cell density in germinative compartment
r Cell birth rate of germinative compartment
GF Growth fraction of germinative compartment
ζ, ξ Dummy variables