Table 2.
Equations relating transit‐amplifying cell density and cell birth rate per unit area of skin surface to stem and transit‐amplifying cell kinetic parameters for asymmetric and symmetric division, with and without apoptosis and with and without variation in number of transit generations
| Division | Lineage variation | Nt | r | ||
|---|---|---|---|---|---|
| Without apoptosis | With apoptosis | Without apoptosis | With apoptosis | ||
| asym | no |
(18) |
(54) |
(20) |
(56) |
| yes |
(63) |
(62) |
(65) |
(64) |
|
| sym | no |
(26) |
(57) |
(28) |
(58) |
| yes |
(69) |
(68) |
(71) |
(70) |
|
The equations for G 1‐8 are given in Table 3, and for α, T̂s, T̂t p s(a), pt(a) and Pi in Table 4. The number in parenthesis after each equation refers to the equation number in the text. These equations have been tested using numerical simulations with uniform and gamma distributions for the cell‐cycle times. The computer code, written in the C programming language, is available from the author.