Table 2.
In utero exposure |
Peripubertal exposure |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metals | Group | Breast Development | Pubic Hair Development | Menarche | Breast Development | Pubic Hair Development | Menarche | ||||||
groupPIP | condPIP | groupPIP | condPIP | groupPIP | condPIP | groupPIP | condPIP | groupPIP | condPIP | groupPIP | condPIP | ||
Ni | 1 | 0.38 | 0.48 | 0.34 | 0.03 | 0.27 | 0.11 | 0.33 | 0.13 | 0.34 | 0.11 | 0.28 | 0.27 |
Cu | 1 | 0.38 | 0.05 | 0.34 | 0.17 | 0.27 | 0.06 | 0.33 | 0.23 | 0.34 | 0.23 | 0.28 | 0.19 |
Mo | 2 | 0.22 | 0.28 | 0.32 | 0.52 | 0.72 | 0.19 | 0.40 | 0.28 | 0.42 | 0.29 | 0.59 | 0.10 |
Ba | 1 | 0.38 | 0.09 | 0.34 | 0.09 | 0.27 | 0.26 | 0.33 | 0.11 | 0.34 | 0.11 | 0.28 | 0.04 |
As | 3 | 0.20 | 0.76 | 0.20 | 0.58 | 0.29 | 0.30 | 0.37 | 0.66 | 0.36 | 0.65 | 0.23 | 0.43 |
Se | 1 | 0.38 | 0.14 | 0.34 | 0.29 | 0.27 | 0.34 | 0.33 | 0.34 | 0.34 | 0.31 | 0.28 | 0.16 |
Al | 1 | 0.38 | 0.16 | 0.34 | 0.24 | 0.27 | 0.03 | 0.33 | 0.03 | 0.34 | 0.10 | 0.28 | 0.05 |
Mn | 2 | 0.22 | 0.26 | 0.32 | 0.17 | 0.72 | 0.71 | 0.40 | 0.31 | 0.42 | 0.32 | 0.59 | 0.08 |
Co | 2 | 0.22 | 0.46 | 0.32 | 0.32 | 0.72 | 0.10 | 0.40 | 0.41 | 0.42 | 0.39 | 0.59 | 0.82 |
Zn | 1 | 0.38 | 0.08 | 0.34 | 0.19 | 0.27 | 0.19 | 0.33 | 0.17 | 0.34 | 0.14 | 0.28 | 0.28 |
Cd | 3 | 0.20 | 0.24 | 0.20 | 0.42 | 0.29 | 0.70 | 0.37 | 0.34 | 0.36 | 0.35 | 0.23 | 0.57 |
Models were adjusted for age and BMI z-score at early teen visit