Table 1.
Patients Characteristics According to Lung Cancer Type
| NSCLC |
SCLC |
||||
|---|---|---|---|---|---|
| Variable | Categories | Summary Statistics |
No. of Studies Providing Data |
Summary Statistics |
No. of Studies Providing Data |
| Total counts | N (%) | 26,430 (100%) | 16 | 2787 (100%) | 16 |
| Age, years | Median (range) | 65 (17–97) | 16 | 65 (22–92) | 16 |
| Year of diagnosis | Median (range) | 2006 (1974–2015) | 16 | 2005 (1987–2015) | 16 |
| Sex, n (%) | Males | 14150 (54%) | 16 | 1561 (56%) | 16 |
| High school graduate | No | 1927 (11%) | 14 | Low: 220 (12%) | 14 |
| Yes | 15,373 (89%) | High: 1643 (88%) | |||
| Missing | 7558 | 897 | |||
| Ethnicity | Caucasian | 18,141 (76%) | 16 | 2484 (93%) | 16 |
| Asian | 3938 (17%) | 59 (2%) | |||
| Black | 1020 (4%) | 33 (1%) | |||
| Other | 686 (3%) | 98 (4%) | |||
| Missing | 2645 | 113 | |||
| Stage | 1A | 5478 (21%) | 16 | – | 16 |
| 1B | 2448 (9%) | – | |||
| 2A | 1131 (4%) | – | |||
| 2B | 1884 (7%) | – | |||
| 3A | 3905 (15%) | – | |||
| 3B | 2434 (9%) | – | |||
| 4 | 9150 (35%) | – | |||
| Limited stage | – | 1135 (41%) | |||
| Extensive stage | 1652 (59%) | ||||
| Histology | Squamous cell | 6024 (23%) | 16 | – | 16 |
| Adenocarcinoma | 15,812 (60%) | – | |||
| Other | 4527 (17%) | – | |||
| Small cell | – | 2787 (100%) | |||
| Missing | 67 | – | |||
| Smoking Status | Ever-smoker | 17,118 (84%) | 14 | 2389 (98%) | 14 |
| Never-smoker | 3201 (17%) | 54 (2%) | |||
| Missing | 3847 | 57 | |||
| Pack years among ever-smokers | Median (range) | 43 (0–275) | 13 | 50 (0.5–200) | 13 |
| Missing | 6304 | 748 | |||
| BMI at diagnosis, kg/mg2 | Median (range) | 25.2 (11-87) | 16 | 26.3 (12-70) | 16 |
| BMI < 18.5 (underweight) | 906 (4%) | 65 (3%) | |||
| 18.5 ≥ BMI < 25 (normal BMI) | 9189 (44%) | 765 (36%) | |||
| 25 ≥ BMI < 30 (overweight) | 7086 (34%) | 815 (38%) | |||
| 40 ≥ BMI ≥ 30 (obese) | 3435 (16%) | 487 (23%)a | |||
| BMI ≥ 40 (morbidly obese) | 321 (2%) | 655 | |||
| Missing | 5493 | ||||
| BMI at young adult age, kg/mg2 | Median (range) | 22.7 (10-71) | 7 | 22.7 (14-43) | 7 |
| BMI < 18.5 (underweight) | 397 (7%) | 31 (6%) | |||
| 18.5 ≤ BMI <25 (normal BMI) | 3518 (65%) | 398 (71%) | |||
| 25 ≤ BMI <30 (overweight) | 1121 (21%) | 95(17%) | |||
| 30 ≤ BMI ≤ 40 (obese) | 378 (7%) | 35 (6%)a | |||
| BMI ≥ 40 (morbidly obese) | 40 (1%) | 134 | |||
| Missing | 943 | ||||
| BMI change from young adult age to diagnosis, kg/mg2 | Decreased BMI | 1639 (30%) | 7 | 112 (20%) | 7 |
| No change/ Increased BMI | 3790 (70%) | 442 (80%) | |||
| Missing | 968 | 139 | |||
a
There were too few morbidly obese individuals to form its own category in SCLC; instead, obese and morbidly obese were grouped together. BMI, body mass index.