Figure 2.

Hyperoxia accelerates the disappearance of the nephrogenic zone in newborn rat kidney. (a) The nephrogenic zone in the kidney of newborn rats, including those from the 3rd (P3D), 5th (P5D), 7th (P7D), and 10th (P10D) postnatal days after exposure to normoxia or hyperoxia and visualized by hematoxylin & eosin (H&E) staining (original magnification ×100; scale bar, 400 μm). Arrows indicate the width of the nephrogenic zone. (b) The width of the neonatal nephrogenic zone, when rats were exposed to normoxia or hyperoxia, is shown (mean ± standard deviation (SD)) by scatter dot plots. The error bars represent the SD of measurements for 10 rats with the mean value of 10 separate fields of view (n = 10). ^∗P < 0.001, one-way ANOVA, Bonferroni post hoc test.