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. 2019 Sep 3;10:750. doi: 10.3389/fgene.2019.00750

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Copyright © 2019 Kalds, Zhou, Cai, Liu, Wang, Petersen, Sonstegard, Wang and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Applications and aims of genome engineering in sheep and goats. Genome engineering has been applied in both sheep and goats (or generally in farm animals) for various purposes such as to investigate the biological and functional roles of genes, to introduce novel economically important traits for agricultural purposes, to produce valuable proteins in milk, to produce animals that are resistant to epidemic diseases, to model human diseases, and to produce hosts for the growth of human organs for xenotransplantation research, among other valuable purposes that mainly aim to increase human knowledge, as well as human and animal health and welfare.