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. 2019 Sep 3;9(1):1657768. doi: 10.1080/20010001.2019.1657768

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Quantification of pTau using the AT8 antibody. (a) FI signals for pTau in RIPA-soluble extracts from frontal cortex in 12-year old dogs (n = 3) and 21-year old vervets (n = 2). (b) FI signals for pTau in RIPA-soluble extracts from frontal cortex in 21-month old wild-type (WT, n = 2) and PS19 mice (n = 3). (c) FI signals for pTau in RIPA-soluble extracts from whole-body worm pellets in WT, CK10 and CK144 worms (each n = 2). As a reference guide, we show averages from previously published [4] findings in AD frontal cortex samples (dashed lines) in panel B. Samples were analyzed with ANOVA followed by post hoc pairwise comparisons. All data are presented as mean ± SEM. ★★ p < 0.01 for post hoc pairwise comparisons.