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. 2019 Sep 3;9(1):1657768. doi: 10.1080/20010001.2019.1657768

Table 1.

Genetic strains of mutant animals used in this study.

Strain/Name Species Mutations Pathology
APPswe/PSEN1dE9 Mus musculus APP (KM670/671NL), PSEN1 (deletion of exon 9) Aβ42 expression in multiple brain regions
CL2659 Caenorhabditis elegans Aβ42 minigene Aβ42 expression in muscle tissue
GMR-GAL4> UAS-Aβ; Tau Drosophila melanogaster Aβ42 minigene,
wild-type MAPT gene
Aβ42 and wild-type Tau expression in eye
PS19 Mus musculus MAPT P301S Phosphorylated Tau in multiple brain regions
CK10 Caenorhabditis elegans MAPT V337M Phosphorylated Tau in neurons
CK144 Caenorhabditis elegans Wild-type MAPT gene Wild-type tau expression in neurons