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. 2019 Aug 14;9(20):5924–5936. doi: 10.7150/thno.36320

Figure 3.

Figure 3

A) Temperature increment for NC@TRAIL (red) and NCs (black) with MDA-MB-231-WT cells in PT mode at 4 mM iron. B) Heating capacity (SLP in W.g-1) of NCs (black) and NC@TRAIL (red) in PT mode. C) MDA-MB-231-WT and DKO (10% FCS) cell death due to the effect of the TRAIL alone ([TRAIL] = 10 nM), NCs and NC@TRAIL at 37 °C and in PT mode. D) Early and late apoptosis and/or necrosis were determined by annexin V and propidium iodide (PI) staining after PT treatment. For each condition the percentage indicated in each compartment represents: viable cells (left, bottom, annexin V- and PI-), early apoptosis (right, bottom, annexin V+ and PI-), late apoptosis and/or necrosis (left, up, annexin V+ and PI+) and the debris (right, up, annexin V- and PI +).