Table 3. Estimated Mean Differences for Various Brain Volumes Among Fighters With and Without CSP and CV.
| Location | Adjusted Mean Difference in Brain Volume, mm3 | |||
|---|---|---|---|---|
| CSP Present vs Absent (95% CI)a,b | P Valuec | CV Present vs Absent (95% CI)a,b | P Valuec | |
| Supratentorium | 21 666 (552 to 42 779) | .31 | −31 191 (−61 903 to −479) | .05 |
| Thalamus | −84 (−420 to 252) | >.99 | −706 (−1188 to −223) | .03 |
| Corpus callosum | 17 (−97 to 131) | >.99 | −234 (−398 to −70) | .03 |
| Caudate | −150 (−369 to 69) | >.99 | −508 (−823 to −193) | .01 |
| Putamen | −49 (−322 to 223) | >.99 | −573 (−965 to −181) | .03 |
| Hippocampus | 27 (−142 to 196) | >.99 | −286 (−530 to −42) | .05 |
| Amygdala | 30 (−64 to 123) | >.99 | −165 (−300 to −29) | .05 |
Abbreviations: CSP, cavum septum pellucidum; CV, cavum vergae.
a
Positive values indicate higher volumes when the imaging finding is present; negative values indicate higher volumes when the imaging finding is absent.
b
Estimates adjusted for age, educational level, race, and ethnicity.
c
Adjusted for multiple comparisons using the Holm step-down method.