. 2019 Sep 9;77(1):35–42. doi: 10.1001/jamaneurol.2019.2861

Table 4. Estimated Change in Mean Brain Volumes With Each 1-mm Increase in CSPV Length.

Location	Estimated Change in Mean Brain Volume per 1-mm Increase in CSPV Length (95% CI), mm^3,^a^,^b	P Value^c
Supratentorium	−1072 (−1655 to −489)	<.001
Thalamus	−22 (−35 to −9)	.005
Corpus callosum	−11 (−16 to −5)	<.001
Caudate	−14 (−24 to −5)	.01
Putamen	−18 (−30 to −6)	.01
Hippocampus	−9 (−16 to −1)	.04
Amygdala	−6 (−10 to −2)	.01

Abbreviation: CSPV, cavum septum pellucidum and cavum vergae.

^{^a}

Positive values indicate higher volumes when CSPV length increases; negative values indicate lower volumes when CSPV length increases.

^{^b}

Estimates adjusted for age, educational level, race, ethnicity, and total intracranial volume.

^{^c}

Adjusted for multiple comparisons using the Holm step-down method.