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. 2019 Sep 10;2019(9):CD003436. doi: 10.1002/14651858.CD003436.pub4

NCT02098252.

Trial name or title Treatment Of Brain AVMS (TOBAS) Study: a randomized controlled trial and registry
Methods International, multicentre, prospective, randomized, controlled, open label, clinical trial
Participants Patients aged ≥18 years diagnosed with a brain AVM
Interventions Management may include interventional therapy (with endovascular procedures, neurosurgery, or radiotherapy, alone or in combination) or conservative management
Outcomes Primary outcome measures
  • death or disabling stroke due to haemorrhage or infarction as revealed by imaging and resulting in mRS > 2


Secondary outcome measures
  • Occurrence of any neurological event

  • Permanent (more than 3 months) disabling (mRS > 2) peri‐operative (within 31 days) complications

Starting date May 2014
Contact information Jean Raymond MD
Notes