TABLE 2.
Factors associated with unfavourable treatment outcomes among first-line TB patients * registered in Sandaun Provincial Hospital and Raihu District Hospital, West Sepik Province, PNG, 1 January 2014–31 December 2016
| Variables | Favourable TB outcome n (%) | Unfavourable TB outcome n (%) | OR (95%CI) | aOR (95%CI) |
|---|---|---|---|---|
| Total | 779 | 240 | ||
| BMU site | ||||
| Raihu District Hospital | 224 (79.7) | 57 (20.3) | Reference | |
| Sandaun Provincial Hospital | 555 (75.2) | 183 (24.8) | 1.30 (0.93–1.81) | 1.41 (1.00–2.01) |
| Sex | ||||
| Female | 374 (75.1) | 124 (24.9) | Reference | |
| Male | 405 (77.7) | 116 (22.3) | 0.86 (0.65–1.15) | 0.86 (0.64–1.15) |
| Age, 5-year increments | – | – | 1.04 (1.00–1.08) | 1.06 (1.02–1.11) |
| Time to BMU site, h | ||||
| <3 | 609 (76.8) | 184 (23.2) | Reference | |
| ⩾3 | 161 (75.2) | 53 (24.8) | 1.09 (0.77–1.55) | 1.05 (0.74–1.51) |
| Not recorded | 9 (75.0) | 3 (25.0) | 1.10 (0.30–4.12) | 1.18 (0.31–4.48) |
| HIV status | ||||
| Negative | 196 (79.4) | 51 (20.6) | Reference | |
| Positive | 8 (57.1) | 6 (42.9) | 2.88 (0.96–8.68) | 2.72 (0.88–8.39) |
| Not recorded | 575 (75.9) | 183 (24.1) | 1.22 (0.86–1.74) | 1.37 (0.92–2.05) |
| Type of TB patient | ||||
| New | 686 (75.5) | 223 (24.5) | Reference | |
| Retreatment | 93 (84.5) | 17 (15.5) | 0.56 (0.33–0.96)† | 0.54 (0.31–0.93)† |
| Site of TB | ||||
| Pulmonary | 445 (76.3) | 138 (23.7) | Reference | |
| Extrapulmonary | 334 (76.6) | 102 (23.4) | 0.98 (0.73–1.32) | 0.81 (0.57–1.15) |
| Classification of TB | ||||
| Bacteriologically confirmed | 213 (78.3) | 59 (21.7) | Reference | |
| Clinically diagnosed | 566 (75.8) | 181 (24.2) | 1.15 (0.83–1.61) | 1.30 (0.84–1.97) |
* Excluding 39 patients who did not have an outcome evaluated.
† P < 0.05.
TB = tuberculosis; OR = odds ratio; CI = confidence interval; aOR = adjusted OR; BMU = Basic Management Unit; HIV = human immunodeficiency virus.