The antitumor effects of DOX/GL-ALG NGPs in H22 hepatocarcinoma tumor-bearing mice. Representative Tumors separated from animals received an intravenous injection of saline, ALG NGPs, GL-ALG NGPs, DOX (4 mg/kg), DOX -ALG NGPs (4 mg/kg), DOX/GL-ALG NGPs (4 mg/kg) (A). Effect of DOX/GL-ALG NGPs on body weight of mice (n=5) (B). Effect of DOX/GL-ALG NGPs on tumor volume (n=5) (C). Sections of the tumor and myocardial tissues taken from animal received an intravenous injection of saline, ALG NGPs, GL-ALG NGPs, DOX (4 mg/kg), DOX-ALG NGPs (4 mg/kg), DOX/GL-ALG NGPs (4 mg/kg) (D).