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. 2019 Jun 25;160(10):2204–2214. doi: 10.1210/en.2019-00186

Figure 3.

Figure 3.

1,25D does not suppress FGF23 signaling in Hyp renal cortex or proximal tubular cells. Western analyses of phospho ERK1/2 (p-ERK1/2) and total ERK1/2 (t-ERK1/2) in (A) renal cortex and (B) proximal tubular cells. The migration of the 43-kDa marker is indicated. Data are representative of that obtained from three mice per group. EGR1 mRNA expression in (C) renal cortex and in (D) proximal tubular cells. Data represents the mean ± SEM. *P < 0.05 vs WT; #P < 0.05 vs Hyp control mice. Hyp C, vehicle-treated Hyp mice; HypD1h, Hyp mice treated with 1,25D for 1 h; HypD18h, Hyp mice treated with 1,25D for 18 h; WT, vehicle-treated WT mice.