Table 1.

Clinical Characteristics in Premenopausal Women

Characteristic	Women With AN (n = 46)	Lean HC (n = 29)	Women With OB (n = 30)	Overall P Value
Age, y	28.9 ± 5.6	28.5 ± 5.7	31.0 ± 7.8	0.31
Body mass index, kg/m2	16.7 ± 1.8a	22.6 ± 1.4b	35.1 ± 3.3c	<0.0001
Physical activity, h/wk	4.1 ± 5.3	6.2 ± 4.9	4.3 ± 4.6	0.21
Appendicular lean mass, kg	14.3 ± 2.1a	18.6 ± 2.2b	22.3 ± 3.9c	<0.0001
Serum IGF-1, ng/mL	177.4 ± 59.0a	221.5 ± 60.4b	184.2 ± 50.8a	0.006
Serum 25(OH)D, ng/mL	31.8 ± 12.7a	22.6 ± 8.4b	19.3 ± 6.7b	<0.0001
Serum 25(OH)D < 20 ng/mL, %	14a	38b	61b	0.0003
Areal BMD
Postero-anterior spine, g/cm2	0.83 ± 0.13a	0.99 ± 0.10b	1.10 ± 0.07c	<0.0001
Postero-anterior spine Z-score	−1.89 ± 1.17a	−0.45 ± 0.87b	0.44 ± 0.71c	<0.0001
Total hip, g/cm2	0.77 ± 0.11a	0.98 ± 0.09b	1.08 ± 0.11c	<0.0001
Total hip Z-score	−1.41 ± 0.88a	0.30 ± 0.75b	0.98 ± 0.86c	<0.0001
Femoral neck, g/cm2	0.65 ± 0.10a	0.85 ± 0.10b	0.94 ± 0.10c	<0.0001
Femoral neck Z-score	−1.68 ± 0.92a	0.02 ± 0.93b	0.74 ± 0.88c	<0.0001
Total radius, g/cm2	0.53 ± 0.06a	0.58 ± 0.04b	0.61 ± 0.05c	<0.0001
Total radius Z-score	−0.71 ± 1.00a	0.19 ± 0.76b	0.71 ± 0.90c	<0.0001

Data are presented as mean ± SD.

^aGroups with different superscripts differ significantly at P ≤ 0.05.

^bGroups with different superscripts differ significantly at P ≤ 0.05.

^cGroups with different superscripts differ significantly at P ≤ 0.05.