Atrophic stage. P5. (A) SW-AF. The lesion is hypoautofluorescent except for punta of hyperautofluorescence inferiorly. (B) NIR-AF. The interior of the lesion is primarily hypoautofluorescent; hyperautofluorescence is present at the lesion edge. (C1–3) SD-OCT scans. A thickening of the RPE/BM reflectivity band in C1 (red arrow) is not autofluorescent in the SW-AF image (A, red arrow) but presents as a bright punctum in the NIR-AF image (B, red arrow). Hyperreflective material corresponding to disorganized IZ in C2 (yellow arrow) is not autofluorescent in the SW-AF (A) and NIR-AF (B) images. The edge of the original lesion, identifiable in (C3) as anterior displacement of EZ, and ELM (blue arrow) presents as autofluorescence in the SW-AF image in (A) but is not visible in the NIR-AF image (B). Increased transmission of OCT signal into the choroid is pronounced in (C3) and inner retina has collapsed into the lesion. The positions of the scans are indicated by green lines in (A). (D, E) qAF color-coded images. Outside the vitelliform lesion in the BVMD patient (D), the qAF levels are similar to that in age-similar healthy eye (E).