Table 2.

Uni- and multivariate Cox-regression analyses for the prediction of overall survival

	Univariate Cox-regression		Multivariate Cox-regression
Parameter	P-value	Hazard ratio (95% CI)	P-value	Hazard ratio (95% CI)
suPAR (>5.956 ng/ml)	0.001	2.304 (1.392–3.813)	0.017	2.533 (1.185–5.418)
Leukocyte count	0.926	0.997 (0.930–1.068)
CRP	0.033	1.006 (1.000–1.011)	0.180	1.005 (0.998–1.013)
Platelets	0.751	1.000 (0.997–1.002)
AST	0.178	1.002 (0.999–1.005)	0.088	1.003 (0.999–1.007)
Bilirubin	0.098	1.051 (0.991–1.116)	0.107	0.916 (0.823–1.019)
ALP	0.873	1.000 (0.999–1.001)
LDH	0.480	0.992 (0.972–1.013)
Creatinine	0.223	1.706 (0.772–4.031)	0.557	1.325 (0.518–3.393)
BMI	0.927	0.998 (0.948–1.050)
ECOG PS	0.221	1.192 (0.899–1.581)	0.251	0.797 (0.540–1.175)
Age	0.059	1.024 (0.999–1.050)	0.198	1.022 (0.989–1.055)
Sex	0.663	0.889 (0.547–1.443)
T-stage	0.271	1.318 (0.807–2.153)

ALP, alkaline phosphatase; AST, aspartate transaminase; BMI, body mass index; CRP, C-reactive protein; ECOG PS, ‘Eastern Cooperative Oncology Group’ performance status; LDH, lactate dehydrogenase.