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. 2019 Jun 28;42(8):284–296. doi: 10.1097/CJI.0000000000000286

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Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/

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In vivo antitumor activity of NK-92-αFR-28BBζ cells. A, Schematic representation of the construction of mouse xenograft model of ovarian cancer and treatment procedures. B, Ovarian cancer development was monitored by in vivo bioluminescence imaging. Images taken at day 0 and day 10 of the experiment are shown. C, Quantification summary of bioluminescence signal intensity in each group shown in (B). The data are expressed as the means±SEM of 5 mice for all groups. *P<0.05; **P<0.01; ns, P≥0.05. D, Kaplan-Meier survival curves of tumor-bearing mice treated with PBS, NK-92 cells, NK-92-EV cells, or NK-92-αFR-28BBζ cells. **P<0.01, compared with the NK-92-αFR-28BBζ group.