Table 8.
Analysis of the association of GSTP1-exon5 and HO-1 (GT)n genotypes with 8-iso-PGF2α concentration, MDA concentration, and CAT activity in the COPD patients
| Gene | 8-iso-PGF2α (mg/L) |
MDA (μmol/L) |
CAT (U/mL) |
|---|---|---|---|
| GSTP1-exon5 | |||
| AA | 25.58±6.35 | 4.23±2.73 | 43.38±5.03 |
| AG | 36.36±6.89★ | 6.45±3.02★ | 34.56±4.25★ |
| GG | 54.18±8.12★& | 9.87±3.38★& | 26.17±3.94★& |
| HO-1 (GT)n | |||
| M*S/M*S | 31.25±5.88 | 5.09±3.14 | 39.23±5.85 |
| L/M*S | 42.67±7.12★ | 6.86±3.89★ | 32.43±5.65★ |
| L/L | 60.39±7.58★& | 11.26±4.12★& | 23.98±5.72★& |
Notes: ★P<0.05 indicates statistical significance, compared with AA of GSTP1-exon5 or M*S/M*S of HO-1 (GT)n. &P<0.05 indicates statistical significance, compared with AG of GSTP1-exon5 or L/M*S of HO-1 (GT)n.