Fig. 2.

(A-C) Assessment of performance of Chemo-GS in independent clinical validation. Chemotherapy is defined as alkylating chemotherapy with or without RT. No chemotherapy is defined as RT alone or no treatment. For visualization purposes, continuous scores are divided into tertiles (low, intermediate, high). (A) Kaplan–Meier curves showing that Chemo-GS is not prognostic in patients who did not receive chemotherapy. (B) Kaplan–Meier curves showing that Chemo-GS is prognostic in patients who received chemotherapy. (C) Interaction plot showing logistic regression models fitting Chemo-GS to 2-year overall survival. Patients with a higher Chemo-GS score derived more benefit from chemotherapy.