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. 2019 Sep 1;11(1):e2019048. doi: 10.4084/MJHID.2019.048

Table 2b.

Details on CMV management and reactivation for recipient of pre-emptive Megalotect infusion (n=78).

Time from HSCT of CMV reactivation, median (range) 29 days (−9 – 399)

Development of CMV disease 7 (9%)

First line anti-CMV therapy
 Ganciclovir 33 (42%)
 Foscarnet 26 (33%)
 Ganciclovir + Foscarnet 3 (3%)
 Valganciclovir 16 (20%)
Need for second or third line of anti-CMV therapy 9 (11%)

Duration of anti-CMV therapy, median (range) 20 days (3–190)

Median dose of Megalotect (range) 50 UI/Kg (10–100)

Schedule
 Every other day 2 (2%)
 Weekly 48 (62%)
 Every 2 weeks 21 (27%)
 Not specified 7 (9%)

Number of administration, median (range) 3 (1–33)

Complete response to anti-CMV therapy 51 (65%)

Subsequent CMV reactivation for responders 14/51 (29%)