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. 2019 Aug 9;34(9):1686–1696. doi: 10.1093/humrep/dez135

Figure 6.

Figure 6

FISH analysis of granulosa cells from individual follicles. The ratio between 46,XX and 45,X granulosa cells from the same small follicle varied considerably. FISH analysis of six individual small follicles from Patient B revealed that the percentage of 45,X granulosa cells varied from 0% to 59% (top row; four follicles are shown). In Patients D (337 granulosa cells from 10 follicles) and E (152 granulosa cells from 5 follicles) all granulosa cells were 45,X. For Patients B and D at least 25 granulosa cells per follicle were analysed and for Patient E at least 22 granulosa cells per follicle.