TABLE 3.
Gene | WT mice | Iron-deficient DNTfR1−/− mice | Iron-replete DNTfR1−/− mice |
---|---|---|---|
Glut1 | 100 ± 4b | 114 ± 3a | 94 ± 4b |
Glut3 | 100 ± 6 | 104 ± 4 | 100 ± 3 |
Hif1α | 100 ± 18b | 247 ± 25a | 168 ± 28b |
Pdh2 | 100 ± 5 | 104 ± 2 | 94 ± 1 |
Values are mean ± SEM percentage changes relative to WT, n = 7 per group. Labeled means in a row without a common letter differ, P < 0.05. DNTfR1−/−, dominant negative transferrin receptor; Glut1, glucose transporter-1 mRNA; Glut3, glucose transporter-3 mRNA; Hif1α, hypoxia inducible factor-1α mRNA; Pdh2, prolyl-hydroxylase-2 mRNA; WT, wild-type.