Table 1.
Testosterone (n = 42) | Placebo (n = 46) | P Value | |
---|---|---|---|
Clinical characteristics | |||
Age, y | 28 ± 7 | 27 ± 7 | 0.29 |
Weight, kg | 49 ± 5 | 50 ± 6 | 0.43 |
BMI, kg/m2 | 18.3 ± 1.8 | 18.3 ± 1.5 | 0.89 |
Duration of AN, y | 12 ± 8 | 11 ± 7 | 0.93 |
AN subtype: restricting/binge-purge, % | 67/33 | 72/28 | 0.65 |
MDD, % | 64 | 59 | 0.66 |
GAD, % | 74 | 67 | 0.64 |
Psychiatric medication use, % | 71 | 76 | 0.64 |
Current amenorrhea, % | 19 | 24 | 0.61 |
Estrogen statusa: replete/deplete, % | 76/24 | 70/30 | 0.47 |
Combination oral contraceptive pill use, % | 17 | 28 | 0.21 |
Hormone measurements | |||
Total testosterone, ng/dL | 26 ± 15 | 24 ± 14 | 0.42 |
Free testosterone, ng/dL | 0.4 ± 0.2 | 0.4 ± 0.2 | 0.85 |
Data are mean ± SD unless otherwise indicated.
Estrogen replete is defined as having menses or taking exogenous estrogen within the last 3 mo, whereas estrogen deplete is defined as having no menses or exogenous estrogen within the last 3 mo.