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. 2019 Aug 8;10(8):e00066. doi: 10.14309/ctg.0000000000000066

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© 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 7. — Validation of the M30 marker for its utility to detect NASH in NAFLD patients with low or intermediate TE values. (a) Most NAFLD patients with low TE values (<7.2 kPa or < 7.9 kPa detected by FibroScan with XL or M probe) but elevated M30 levels (>200 U/L) revealed histological NASH with fibrosis in the validation cohort. (b) NASH could also be detected in most NAFLD patients with intermediate (7.9/7.2–9.6/9.3 kPa for M/XL probe) TE values and enhanced M30 levels, and most of them revealed fibrosis. NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; TE, transient elastography.