Table 3.
The performance of different laboratory markers in EOS diagnosis.
| Parameters | AUC | Cutt of value | Sensitivity % | Specificity % | LR+ | PPV % | NPV % | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group 1 | Group 2 | Group 1 | Group 2 | Group 1 | Group 2 | Group 1 | Group 2 | Group 1 | Group 2 | Group 1 | Group 2 | Group 1 | Group 2 | |
| PLR | 0.812 | 0.847 | 39.5 | 57.7 | 88.9 | 91.3 | 94.7 | 97.6 | 16 | 9.2 | 94.3 | 97.4 | 88.6 | 91.8 |
| CRP (mg/L) | 0.88 | 0.913 | 4.5 | 7.2 | 72.7 | 87.9 | 69.1 | 71.3 | 4.7 | 8.3 | 70.1 | 75.3 | 71.6 | 86.5 |
| PCT (ng/ml) | 0.827 | 0.865 | 0.8 | 2.2 | 69.4 | 83.4 | 96.3 | 98.8 | 11.2 | 19.3 | 94.9 | 98.5 | 75.8 | 85.6 |
| I/T ratio | 0.947 | 0.955 | 0.18 | 0.22 | 45.6 | 54.3 | 96.7 | 98.1 | 16.3 | 12.5 | 93.2 | 96.6 | 30.1 | 68.2 |
Group 1: Suspected Early Onset Neonatal Sepsis; Group 2: Proven Early Onset Neonatal Sepsis; PLR, platelet to lymphocyte ratio; CRP, C-reactive protein; PCT, Procalcitonin; I/T, immature to total neutrophil; LR+, Likelihood Ratio; PPV, Positive predictive value; NPV, Negative predictive value.