Table 2. List of identified proteins showing differential expression between normal and prediabetes/diabetes groups.
| Protein ID a) |
Gene name | Description | Acc. no. b) | Nominal mass (Mr) c) |
Calculated PI | Score d) |
|---|---|---|---|---|---|---|
| 31 | ND e) | |||||
| 157 | C1NH | C1-inhibitor, partial | AAA51848.1 | 32745 | 8.85 | 72 |
| 197 | ALB | PRO2619 | AAG35503.1 | 58513 | 5.96 | 114 |
| 235 | SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary), isoform CRA_a | EAW73762.1 | 45526 | 6.01 | 68 |
| 356 | ALB | albumin, isoform CRA_h | EAX05666.1 | 70564 | 5.92 | 223 |
| 379 | ALB | PRO2619 | AAG35503.1 | 58513 | 5.96 | 221 |
| 386 | GIG25 | growth-inhibiting protein 25 | AAT08029.1 | 32857 | 5.71 | 165 |
| 396 | GIG25 | growth-inhibiting protein 25 | AAT08029.1 | 32857 | 5.71 | 110 |
| 405 | GIG25 | growth-inhibiting protein 25 | AAT08029.1 | 32857 | 5.71 | 90 |
| 414 | ND | |||||
| 417 | AHSG | alpha-2-HS-glycoprotein isoform 4 preproprotein | NP_001341502.1 | 37010 | 5.41 | 78 |
| 425 | AHSG | alpha-2-HS-glycoprotein, isoform CRA_a | EAW78187.1 | 39970 | 5.43 | 87 |
| 446 | SERPINA1 | Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | AAH11991.1 | 46864 | 5.36 | 139 |
| 461 | SERPINA1 | Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | AAH15642.1 | 46850 | 5.37 | 104 |
| 473 | DKFZp686N02209 | hypothetical protein | CAD98026.1 | 53503 | 8.74 | 146 |
| 481 | ALB | albumin, isoform CRA_k | EAX05669.1 | 48568 | 5.97 | 87 |
| 492 | ALB | PRO2675 | AAF69644.1 | 33466 | 6.14 | 101 |
| 511 | HP | HP protein | AAH70299.1 | 31647 | 8.48 | 141 |
| 527 | HP | HP protein | AAH70299.1 | 31647 | 8.48 | 110 |
| 531 | HP | HP protein | AAH70299.1 | 31647 | 8.48 | 150 |
| 551 | HP | HP protein | AAH70299.1 | 31647 | 8.48 | 156 |
| 553 | HP | HP protein | AAH70299.1 | 31647 | 8.48 | 159 |
| 554 | ZAG | zinc-alpha2-glycoprotein precursor | BAA14417.1 | 34079 | 5.57 | 173 |
| 557 | HP | HP protein | AAH70299.1 | 31647 | 8.48 | 82 |
| 696 | ND | |||||
| 714 | APCS | serum amyloid P-component precursor | NP_001630.1 | 25485 | 6.10 | 104 |
| 725 | IgG kappa chain, partial | BAA37169.1 | 23690 | 6.92 | 112 | |
| 737 | IgG kappa chain, partial | BAA37169.1 | 23690 | 6.92 | 114 | |
| 754 | APOA1 | apolipoprotein A-I isoform 1 preproprotein | NP_000030.1 | 30759 | 5.56 | 230 |
| 756 | APOA1 | apolipoprotein A-I isoform 1 preproprotein | NP_000030.1 | 30759 | 5.56 | 179 |
| 760 | APOA1 | apolipoprotein A-I isoform 1 preproprotein | NP_000030.1 | 30759 | 5.56 | 192 |
| 852 | RBP4 | Retinol binding protein 4, plasma | AAH20633.1 | 23371 | 5.76 | 140 |
| 905 | ND | |||||
| 913 | HP | haptoglobin, partial | ALX40934.1 | 13744 | 6.10 | 76 |
| 976 | TTR | Transthyretin | ABI63345.1 | 20300 | 5.16 | 76 |
| 979 | TTR | transthyretin precursor | NP_000362.1 | 15991 | 5.52 | 137 |
| 1050 | ND | |||||
| 1075 | APOA2 | apolipoprotein A-II, isoform CRA_d, partial | EAW52622.1 | 10630 | 9.10 | 112 |
| 1081 | unnamed protein product | BAG51195.1 | 15846 | 6.06 | 77 |
a) Protein IDs correspond to the numbers in 2DE images in Fig 1A.
b) Acc. no. is the NCBInr database accession number.
c) The nominal mass is the integer mass of the most abundant naturally occurring stable isotope of an element. The nominal mass of a molecule is the sum of the nominal masses of the elements in its empirical formula.
d) Protein score is -10 × Log (P), where P is the probability that the observed match is a random event. Protein scores of greater than 62 are significant (p < 0.05).
e) ND: not detected.