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. 2019 Sep 10;13(9):e0007368. doi: 10.1371/journal.pntd.0007368

Fig 2. Circulating NETs components are higher in T2R patients, which decrease after thalidomide treatment.

Fig 2

Patient serum samples were obtained; and the levels of the DNA-histone (A, B) and DNA-MPO (C, D) complexes were quantified by ELISA. DNA-MPO complex levels are expressed as percentages values above the blank. (B, D) Follow-up of the complexes serum levels during thalidomide treatment. Outliers were removed from analysis. Box plots show median, interquartile range, sample minimum, and maximum. Each dot represents a donor. **P<0.01 (Mann Whitney test). (E) Spearman’s correlation between DNA-histone and DNA-MPO complexes per patient (n = 36, r = 0.5247, P = 0.001).