Fig 3. Distribution of the estimated loss of LECA Pfam domains in proteomes shown by white bars, with the median loss given by the black vertical line.

The Dollo parsimony approach places 4182 Pfams in LECA. These LECA Pfams have been lost independently 111320 times. A large number of Pfams are conserved in all current day species (never lost). Distributions of the corrected loss of LECA Pfam domains from six-frame translated genomes are shown by orange coloured bars, with the corrected median loss given by the red vertical line. The inset shows the difference in distributions of the six-frame translated genomes minus the proteomes.