Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Illustration of the P-glycoprotein (P-gp) interaction with bumped kinase inhibitors (BKIs) in the gastrointestinal tract. A, Low absorption of BKI1318 into the enterocyte as a result of P-gp–mediated efflux. B, In the presence of the P-gp inhibitor elacridar, BKI1318 absorption into the intestinal epithelium allows for targeting of Cryptosporidium.
