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. 2019 Jun 7;171(1):221–234. doi: 10.1093/toxsci/kfz136

Figure 6.

Figure 6.

Functional enrichment analysis of genes DE with BDE-47 in NPCs. (A). Enriched GO Biological Processes within BDE-47 DE Genes identified using DAVID (criteria: p < .01, number of DE genes associated with enriched term ≥ 7). GO enrichment scores [−log (p)] are displayed for all BDE-47 DE Genes and upregulated (Cluster I) or downregulated (Cluster II) gene subsets. The total number of DE Genes due to BDE-47 is located in parentheses (up, downregulated). Clustering of BDE-47 DE Genes associated with terms: (B) Response to Hormone, (C) Steroid Metabolism, (D) Neurogenesis, (E) Response to Oxidative Stress, and (F) Mitotic Nuclear Division. FC values represent average difference between BDE-47 and vehicle control.