Table 2.

Number of Replicates in Each Drug Experiment

Mouse Strain	M+B+T Dose (mg/kg), or Vehicle	BLE* Parameters	n (OCT/Flat Mount)	Data Presented
Gnat1−/−	Vehicle	12.5 klux, 0.5 hours	7/7	Figure 3M/N
Gnat1−/−	0.2-0.02-0.01	12.5 klux, 0.5 hours	6/7	Figure 3M/N
Gnat1−/−	1-0.1-0.05	12.5 klux, 0.5 hours	6/5	Figure 3M/N
Gnat1−/−	10-1-0.5	12.5 klux, 0.5 hours	5/4	Figure 3M/N
Gnat1−/−	Vehicle	25 klux, 1 hour	5/4	Figure 3O/P
Gnat1−/−	10-1-0.5	25 klux, 1 hour	5/4	Figure 3O/P
Gnat1−/−	50-5-2.5	25 klux, 1 hour	4/4	Figure 3O/P
Grk1−/−	Vehicle	12.5 klux, 0.5 hours	6/7	Figure 4A/E
Grk1−/−	1-0.1-0.05	12.5 klux, 0.5 hours	6/6	Figure 4A/E
Grk1−/−	10-1-0.5	12.5 klux, 0.5 hours	6/7	Figure 4A/E
Grk1−/−	50-5-2.5	12.5 klux, 0.5 hours	5/5	Figure 4A/E
Arr1−/−	Vehicle	12.5 klux, 0.5 hours	8/7	Figure 5A/E
Arr1−/−	1-0.1-0.05	12.5 klux, 0.5 hours	5/5	Figure 5A/E
Arr1−/−	10-1-0.5	12.5 klux, 0.5 hours	6/6	Figure 5A/E
Arr1−/−	30-3-1.5	12.5 klux, 0.5 hours	5/5	Figure 5A/E

ONL thickness is an average of two eyes, whereas cone preservation analysis is from one eye per mouse.

^*BLE, bright light exposure at an average exposure intensity of 12.5 or 25 klux, and 0.5- or 1-hour duration.