Table 2.
Multivariable Models of Body Size Across the Life Course and Benign Breast Disease Diagnosis, Early Determinants of Mammographic Density Study, United States, 1959–2008
| Exposure | Age- and Site-Adjusted | Multivariable-Adjusted | ||
|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |
| Model 1: maternal prepregnancy BMI, per unit increasea | 0.96 | 0.92, 1.00 | 0.97 | 0.93, 1.02 |
| Model 2: gestational weight gain, per 1-kg increaseb | 1.01 | 0.97, 1.04 | 1.00 | 0.96, 1.04 |
| Model 3: ponderal index at birth, per unit increasec | 0.96 | 0.92, 1.01 | 0.96 | 0.91, 1.02 |
| Model 4: BMI at age 1 year, per unit increased | 1.01 | 0.92, 1.11 | 1.05 | 0.95, 1.16 |
| Model 5: BMI at age 4 years, per unit increased | 0.93 | 0.85, 1.03 | 0.95 | 0.86, 1.06 |
| Model 6: BMI at age 7 years, per unit increased | 0.92 | 0.84, 1.00 | 0.93 | 0.84, 1.03 |
| Model 7: BMI during ages 20–29 years, per unit increased | 0.95 | 0.90, 0.99 | 0.96 | 0.92, 1.01 |
Abbreviations: BMI, body mass index; CI, confidence interval; OR, odds ratio.
a BMI was calculated as weight (kg)/height (m)2. Multivariable model adjusted for site, age at interview, race/ethnicity, maternal age at registration, maternal education, maternal height, maternal cigarettes per day, and family history of breast cancer.
b Multivariable model adjusted for everything in model 1 plus maternal prepregnancy BMI and prematurity.
c Ponderal index was calculated as weight (kg)/height (m)3. Multivariable model adjusted for everything in model 2 plus gestational weight gain.
d BMI was calculated as weight (kg)/height (m)2. Multivariable model adjusted for everything in model 3 plus ponderal index at birth.