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. Author manuscript; available in PMC: 2019 Sep 10.
Published in final edited form as: Reprod Toxicol. 2018 Mar 8;78:50–59. doi: 10.1016/j.reprotox.2018.03.003

Table 2.

Intraductal hyperplasias are observed in BPS- and EE2-treated females in adulthood

Treatment group Number of females evaluated Incidence of intraductal hyperplasia (%) p-value, Chi Square compared to controls
Controls 23 1/23 (4%)
2 μg BPS/kg/day 16 8/16 (50%) p<0.01
200 μg BPS/kg/day 13 8/13 (62%) p<0.01
0.01 μg EE2/kg/day 16 9/16 (56%) p<0.01
1 μg EE2/kg/day 11 7/11 (64%) p<0.01