Table 3.

Gender, pre- and post-operative acid output measurements and durations of disease, cure and drug withdrawal in 12 patients who were unable to discontinue all antisecretory therapy

		Pre-operative				At withdrawal
Patient	Gender	Disease duration (years)	BAO (mmol/h)	MAO (mmol/h)	BAO/MAO ratio	Time after surgery (months	BAO (mmol/h)	MAO (mmol/h)	BAO/MAO ratio	Time off all medicine (months)
17	M	9.5	66	97	0.7	77	6	ND†	—	0.5
18	F	17.8	28	60	0.5	17	6	35	0.2	0.5
19	M	5.9	41	65	0.6	16	16	62	0.3	0.5
20	M	1.2	63	105	0.6	5	19	74	0.3	0.5
21*	F	1.5	15	42	0.4	19	6	16	0.4	0.5
22	M	10	95	127	0.7	40	7	53	0.1	0.5
23	M	22.3	24	80	0.3	14	17	80	0.2	0.25‡
24	M	2.3	16	56	0.3	70	13	42	0.3	0.5
25	F	3.7	22	40	0.6	62	10	40	0.3	0.5
26	F	1.3	38	38	1.0	83	11	29	0.4	0.1‡
27	M	26.5	52	81	0.6	53	10	51	0.4	1
28	M	7.5	31	46	0.7	68	6	26	0.2	0.5
Mean ± S.E.M.		9.1 ± 2.5	41 ± 7	70 ± 8	0.58 ± 0.06	44 ± 8	11 ± 1	46 ± 6	0.3 ± 0.03	0.48 ± 0.02
Range		1.2–26.5	15–95	23–127	0.3–1.0	5–83	6–19	16–80	0.1–0.4	0.1–1

^*Previous partial gastrectorny.

^†Not done—MEN-2 with medullary thyroid carcinoma, pentagastrin injection deemed to be unsafe.

^‡Unable to tolerate antisecretory drug withdrawal for 2 full weeks due to the development of severe symptoms of gastric acid hypersecretion.