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. Author manuscript; available in PMC: 2019 Sep 10.
Published in final edited form as: Regul Pept. 2002 Nov 15;109(1-3):115–125. doi: 10.1016/s0167-0115(02)00194-5

Fig. 3.

Fig. 3.

Stimulation of adenylyl cyclase. cAMP response was determined in HCT8 cell line as a function of PACAP-38 concentration. The percent maximal responses above basal is shown. A 12-fold increase in cAMP levels were observed for maximal 1 aM PACAP-38 stimulation with a half-maximal effective dose (EC50) of 3.0 nM. These data represent the means of three experiments performed in triplicate.