Table 3.
VEGF mRNA
Addition | Percentage VEGF mRNA |
---|---|
None | 100±8 |
PACAP-27, 100 nM | 194±13 ** |
VIP, 100 nM | 152±11 * |
PACAP-27 + PACAP(6–38) | 135±14 * |
VIP + PACAP(6–38) | 157±15 * |
PACAP+ 50 µM H89 | 144±15 * |
VIP + H89 | 112±9 |
PACAP-27 + 10 µM PD98059 | 141±12 * |
VIP + PD98059 | 144±9 * |
Agents were added to NCI-H1299 cells at the indicated concentrations and the RNA extracted after 8 h. The relative percentage VEGF mRNA (mean ± S.D. of four determinations) is indicated; using Student’s t-test.
p < 0.05.
p < 0.01.