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. Author manuscript; available in PMC: 2019 Sep 10.
Published in final edited form as: Gastroenterology. 2000 Apr;118(4):696–704. doi: 10.1016/s0016-5085(00)70139-9

Figure 2.

Figure 2.

Gastric acid output curves after IV pantoprazole in 4 representative ZES patients. For 17 of 21 patients (81% of the study cohort), acid secretion was controlled with 80 mg IV pantoprazole every 12 hours (a representative example of this pattern of control is shown in A). Two patients (9.5%) required 120 mg IV pantoprazole every 12 hours (a representative example of this pattern of control is shown in B). (Cand D) Two patients (9.5%) required 80 mg IV pantoprazole every 8 hours. (C)The patient’s condition was uncontrolled with twice daily therapy, but after the study protocol was amended to permit dosing every 8 hours, control was achieved rapidly. (D) The dose interval was shortened to 8 hours in a patient after the first control measurement showing loss of control with immediate results.