Table 3.
Maintenance Dose Requirements
| Variable | Sporadic ZES (n = 14) | ZES + MEN-I (n = 7) | Total (n = 21) |
|---|---|---|---|
| Initial acid output (mEq/h) | |||
| Mean (SD) | 49.2 (30.1) | 22.1 (7.7) | 40.2 (27.9) |
| Range | 15.2–117.9 | 11.2–33.1 | 11.2–117.9 |
| Acid output at evaluabilitya (mEq/h) | |||
| Mean (SD) | 1.9 (2.3) | 1.6 (1.2) | 1.8 (2.0) |
| Range | 0.0–7.4 | 0.6–4.1 | 0.0–7.4 |
| Patients controlled (n) | |||
| 80 mg every 12 h | 12 | 5 | 17 |
| 120 mg every 12 h | 1 | 1 | 2 |
| 80 mg every 8 h | 1 | 1 | 2 |
| Total patients controlled (N) | 14 | 7 | 21 |
a
Evaluability is defined as the time point at which acid output had been controlled for the previous 24 hours, i.e., the time point at which efficacy was reached.