Table 4.

IV Pantoprazole Offset

Population	Acid output (mEq/h)
	At end of last dose interval	1 hour later	3 hours later	5 hours later
Sporadic ZES (n)	13	13	12	9
Mean (SD)	2.6 (2.9)	3.0 (3.7)	5.2 (6.5)	3.4 (3.7)
Range	0.0–7.9	0.0–12.0	0.0–21.5	0.0–9.7
ZES + MEN-I (n)	6	6	6	6
Mean (SD)	2.6 (2.6)	2.6 (2.4)	4.1 (3.4)	5.0 (3.5)
Range	0.1–7.4	0.2–6.5	0.0–10.1	0.0–8.3
Total (n)	19	19	18	15
Mean (SD)	2.6 (2.7)	2.8 (3.3)	4.9 (5.6)	4.0 (3.6)
Range	0.0–7.9	0.0–12.0	0.0–21.5	0.0–9.7

NOTE. After the last infusion of pantoprazole, acid output was measured at the end of the last dose interval, starting from 1 hour before the next normally scheduled dose, and continued for the next 5 hours or until acid output reached either 50% of the previously measured approximate BAO or a rate ≥10 mEq/h.