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. 2019 Aug 21;10:1920. doi: 10.3389/fimmu.2019.01920

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Copyright © 2019 Lackner, Weber, Baur, Haffner-Luntzer, Eiseler, Fois, Gebhard, Relja, Marzi, Pfeifer, Halvachizadeh, Lipiski, Cesarovic, Pape, Kalbitz and TREAT Research Group.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Calcium handling of human cardiomyocytes. Delta calcium peaks (msec) of human cardiomyocytes treated for 30 min with 100 ng/ml Midkine (A). Frequency of calcium signals (sec) of human cardiomyocytes treated for 60 min with 100 ng/ml Midkine (B). Traces of calcium signals of human cardiomyocytes (Mean Calcium peaks of ration of interest (ROI) vs. time in sec) (C,D). Traces of calcium signals of human cardiomyocytes (Ratio of Fura-2 signals in A.U. vs. time in sec) (E,F). Different colors for selected ROI of calcium signals of the cells. For all experiments n = 6. Results are presented as mean ± SEM. Data were analyzed by one-way ANOVA followed by Dunnett's or Tukey's multiple comparison test. Results are significant *p < 0.05.