Table 2.
Odds ratios of the association between index serrated polyps (n = 918) and advanced colorectal neoplasia according to histology, size, location, and number of serrated polyps
| Cases n (%) | Controls n (%) | Adjusted ORa (95% CI) | |
|---|---|---|---|
| Histology | |||
| HPs only | 39 (67) | 662 (77) | 1.00 (Ref) |
| SSA/Ps | 19 (33) | 198 (23) | 1.79(0.98–3.28) |
| Size | |||
| All < 10mm | 43 (74) | 632 (73) | 1.00 (Ref) |
| Any 10 +mm | 6 (10) | 87 (10) | 0.95 (0.38–2.34) |
| Location | |||
| Rectum/Rectosig | 11(19) | 235 (27) | 1.00 (Ref) |
| Left | 17 (29) | 192 (22) | 1.62(0.73–3.60) |
| Right | 24 (41) | 334 (39) | 1.64(0.75–3.58) |
| Number of serrated polyps | |||
| 1 | 40 (69) | 650 (76) | 1.00 (Ref) |
| 2 | 13 (22) | 138 (16) | 1.49 (0.78–2.87) |
| 3 | 3 (5) | 46 (5) | 1.19 (0.35–4.02) |
| 4 + | 2 (3) | 26 (3) | 1.46 (0.34–6.32) |
Adjusted for age at index (continuous), sex, BMI (continuous with multiple imputation), smoking status (never vs. ever with multiple imputation), and year between index and subsequent procedure